- Handling of gaseous reagents
- Selective catalytic hydrogenation
- Use of fruorinating reagents:
– Trifluoromethyl diazomethane
– SF4 in HF
– Antimony trifluoride
– DAST, Morpho-DAST, Deoxo-Fluor
– Alkylation with CF3I, Halothane, Freon-113
- Multigram scale photochemistry
- Handling of flammable reducing agents:
– LAH, DIBAL, AlH3, Vitride, L-Selectride, Super-Hydride, BH3
- Use of flammable strong bases:
– LiHMDS, n-BuLi, s-BuLi, t-BuLi, MeLi, LDA, LTMP
- Use of Mg, Al and Zn organo-derivatives
- Handling of toxic organotin derivatives
- Handling of Hg, Bi, Cd-reagents
- Chemistry in liquid ammonia